FWIW there are/were some after-market flushing devices that significantly improved the flushing capability by adding either more pressure or a pulsing action. One of those marketed a product called 'MST Guardian' and the write-ups on it and indpendent testing appeared to bt extremely positive. But the MST company itself now seems to be in a brutal lawsuit regarding the principles of the company and 'who' owns the intellectual property rights.
To your post inquiry - their testing showed that some std flushing on hoses is useless at worst to marginal at best, due to flow and pressure issues. But also for 'time'. If I recall correctly, they are the ones who said a 'good' hose (meaning adequate flow & pressure) had to be put onto a motor for at least 20-minutes to a half hour to get any sign of positive results.
Harm? Even with the higher-pressured aftermarket devices in use, I never heard of any harm every being done.
That said ... I've never flushed a motor in 40-years+ of boating, but I believe my circumstances are unique. As I'm on a tidal river and up-river the water is brackish, which is fresh water flowing to the saltwater estuary. I've never encountered salt build-up leading to a detrimental effect.
Regardless if you flush or not, one should still do a full waterpump service to include the impeller, and thermostats every 2-3 seasons, maybe annually with heavy use. As with anything boating ... your mileage will vary.