I've made the switch to a 2 micron and have been running it for about a season and a half without any problems. I run a 1999 Yamaha 0X66.
I had been accumulating that fine gray powder in my VST filter, but was cleaning it out every 100 hours to stay ahead of it and prevent any problems. Now with the 2 micron I feel comfortable cleaning it at the beginning of the season and running it the whole season (average 175-200 engine hours).
I'm not a mechanic, but I believe the potential engine problems could be caused if there is any restriction in the fuel delivery system, generating too much of a vacuum for the low pressure pumps to pull fuel into the engine.
The excessive vacuum could be caused by a clogged filter, accumulated gunk at the fuel pickup tube or anti-siphon valve, etc.. or any combination of the above.
Some people have been successful attaching a fuel vacuum gauge directly onto unused ports on the base of the fuel / water separator to keep an eye on things.
Since its a spin-on replacement for your existing filter, its a no-brainer to try it out if the rest of your engine & fuel delivery system has been properly maintained.
-- Tom