This is on my 2320 F/250, should at least give you an idea.
Stock black painted stainless Yamaha 3 blade 19p. Hole shot stunk, cruise MPG was like 1.7 with a decent load and clean bottom, 4800 rpm around 26 mph. Also could only get about 5400 rpm with a heavy load.
Switched to a OSI Turbo 4 blade 17p. Now have a great hole shot, cruise mpg went up to 2.2 with a decent load and clean bottom. Can stay on plane at lower speeds but lost a few mph off the top end but I don't care about that. I also now see 6000 rpm top end with load.
Overall I run a very heavy boat usually fishing 4 guys, 2 anchors with 1000 feet of rode each, extra anchor and chain, 25 plus pound of sinkers, ect.... and I average just about 2.0 mpg overall with the 4 blade and I am very happy with it. Mid range torque was also a major improvement with the 4 blade.