I just finished up a 6-month+ shop for used Yamaha 200s. Looked at carbed, OX66 and HPDI. Of the three, the HPDIs had by far the highest number of powerhead replacements. Maybe there's just more out there, or they get used harder, but that definitely played a role in my decision.
Carbed I wasn't excited about. The rep. as the oldest technology out there w/ the worst fuel economy did them in.
So, I ended up with a pair of '00 200 OX66s w/ under 100 hours. Based on my research they seemed to be the best blend of performance, economy and reliabilty. Getting them ready for rigging on my Grady now.
Given the three you mentioned, I would pick the 4-strokes.